Lipoxamycin hemisulfate

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

Lipoxamycin hemisulfate 是一种抗真菌抗生素和有效的丝氨酸棕榈酰转移酶抑制剂，IC50 为 21 nM。

Lipoxamycin has antifungal activity against a panel of humanpathogenic fungi with better potency against some of the Candida species (MIC values, 0.25-16 μg/mL). Cryptococcus neoformans is the most sensitive organism, followed by various species of Candida. Other filamentous fungi are sensitive to the Lipoxamycin in disk diffusion assays.Lipoxamycin has a long alkyl chain and an amino-containing polar head group. Lipoxamycin is on the same order of potency as the sphingofungins and also have potent activity against the mammalianenzyme.

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Microbiology/Virology

Fungal

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11075-87-9

421.54

C??H??N?O?.?/?H?O?S

>98% (HPLC)

DMSO : 40 mg/mL (94.89 mM; ultrasonic and warming and heat to 60°C)

OC[C@@H](C(N(O)CCC(CCCCCCC(CCCC(C)C)=O)=O)=O)N.OS(O)(=O)=O.[1/2]

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(-20℃)

With Ice Pack

≥ 2 years